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Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors
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SYSNO ASEP 0455915 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors Author(s) Fajtová, P. (CZ)
Štefanić, S. (CH)
Hradilek, M. (CZ)
Dvořák, Jan (BC-A)
Vondrášek, J. (CZ)
Jílková, A. (CZ)
Ulrychová, L. (CZ)
McKerrow, J.H. (US)
Caffrey, C.R. (US)
Mareš, M. (CZ)
Horn, M. (CZ)Source Title PLoS Neglected Tropical Diseases. - : Public Library of Science - ISSN 1935-2735
Roč. 9, č. 6 (2015), e0003827Number of pages 24 s. Publication form Online - E Language eng - English Country US - United States Keywords Schistosoma mansoni ; schistosomiasis ; prolyl oligopeptidase ; blood fluke Subject RIV EB - Genetics ; Molecular Biology Institutional support BC-A - RVO:60077344 UT WOS 000357398100031 DOI 10.1371/journal.pntd.0003827 Annotation Blood flukes of the genus Schistosoma cause schistosomiasis, a parasitic disease that infects over 240 million people worldwide, and for which there is a need to identify new targets for chemotherapeutic interventions. Our research is focused on Schistosoma mansoni prolyl oligopeptidase (SmPOP) from the serine peptidase family S9, which has not been investigated in detail in trematodes. Workplace Biology Centre (since 2006) Contact Dana Hypšová, eje@eje.cz, Tel.: 387 775 214 Year of Publishing 2016
Number of the records: 1