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The combination of meltblown and electrospinning for bone tissue engineering
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SYSNO ASEP 0452110 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title The combination of meltblown and electrospinning for bone tissue engineering Author(s) Erben, J. (CZ)
Pilařová, K. (CZ)
Sanetrník, F. (CZ)
Chvojka, J. (CZ)
Jenčová, V. (CZ)
Blažková, L. (CZ)
Havlíček, J. (CZ)
Novák, O. (CZ)
Mikeš, P. (CZ)
Prosecká, Eva (UEM-P)
Lukáš, D. (CZ)
Kuželová Kostaková, E. (CZ)Number of authors 12 Source Title Materials Letters. - : ELSEVIER SCIENCE BV - ISSN 0167-577X
Roč. 143, mar 15 (2015), s. 172-176Number of pages 5 s. Language eng - English Country NL - Netherlands Keywords meltblown ; electrospinning ; tissue engineering ; polycaprolactone Subject RIV JI - Composite Materials Institutional support UEM-P - RVO:68378041 UT WOS 000350520200046 EID SCOPUS 84920692730 DOI 10.1016/j.matlet.2014.12.100 Annotation Materials combining meltblown and electrospinning products with hydroxyapatite powder as potential scaffolds for bone tissue engineering are presented here. The combination of these technologies and parameters and final micro-nanofibrous products are introduced too. The in-vitro testing compared meltblown material, meltblown material with sputtered particles, meltblown material combined with electrospun fibers, meltblown material combined with electrospun fibers and sputtered particles. All the fibrous materials are produced from polycaprolactone. The first in-vitro tests showed the high potential of developed composite materials in bone tissue engineering. The structure of the tested materials allows osteoblasts to proliferate into the sample inner structure with the significant contribution of nanofiber content to cell proliferation. (C) 2015 Elsevier B.V. All rights reserved. Workplace Institute of Experimental Medicine Contact Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Year of Publishing 2016
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