Number of the records: 1

Effect of low doses of herbicide paraquat on antioxidant defense in Drosophila

SYSNO ASEP	0451715
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Effect of low doses of herbicide paraquat on antioxidant defense in Drosophila
Author(s)	Krůček, Tomáš (BC-A) Korandová, Michala (BC-A) Szakosová, K. (CZ) Šerý, Michal (BC-A)_ORCID Čapková Frydrychová, Radmila (BC-A)_{RID, ORCID}
Number of authors	5
Source Title	Archives of Insect Biochemistry and Physiology. - : Wiley - ISSN 0739-4462 Roč. 88, č. 4 (2015), s. 235-248
Number of pages	14 s.
Language	eng - English
Country	US - United States
Keywords	Drosophila ; oxidative stress ; paraquat
Subject RIV	CE - Biochemistry
R&D Projects	GA14-07172S GA ČR - Czech Science Foundation (CSF)
Institutional support	BC-A - RVO:60077344
UT WOS	000351682200003
EID SCOPUS	84925326088
DOI	10.1002/arch.21222
Annotation	Despite a high toxicity, paraquat is one of the most widely used herbicides in the world. The study evaluated the effect of paraquat exposure on antioxidant response in Drosophila melanogaster. When we examined the /nenzymatic activity of superoxide dismutase and catalase in flies exposed to a wide range of paraquat concentrations (0.25 μM to 25 mM), biphasic dose–/nresponse curve with the peak at 2.5 μM paraquat was revealed. Males revealed higher susceptibility to paraquat exposure, displaying higher lethality, increased levels of superoxide dismutase activity, and increased peroxide /nlevels than found in females. Because susceptibility to paraquat was enhanced by mating, the study supports the hypothesis of elevation of stress sensitivity as a physiological cost of reproduction.
Workplace	Biology Centre (since 2006)
Contact	Dana Hypšová, eje@eje.cz, Tel.: 387 775 214
Year of Publishing	2016
Electronic address	http://onlinelibrary.wiley.com/doi/10.1002/arch.21222/epdf

Number of the records: 1