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Non-thermal plasma mills bacteria: scanning electron microscopy observations

SYSNO ASEP	0448062
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Non-thermal plasma mills bacteria: scanning electron microscopy observations
Author(s)	Lunov, Oleg (FZU-D)_ORCID Churpita, Olexandr (FZU-D)_{RID, ORCID} Zablotskyy, Vitaliy A. (FZU-D)_RID Deyneka, I.G. (RU) Meshkovskii, I.K. (RU) Jäger, Aleš (FZU-D)_{RID, ORCID} Syková, Eva (UEM-P)_RID Kubinová, Šárka (FZU-D)_{RID, ORCID} Dejneka, Alexandr (FZU-D)_{RID, ORCID}
Source Title	Applied Physics Letters. - : AIP Publishing - ISSN 0003-6951 Roč. 106, č. 5 (2015), "053703-1"-"053703-5"
Number of pages	5 s.
Language	eng - English
Country	US - United States
Keywords	non-thermal plasma ; plasma medicine ; bacteria ; cells
Subject RIV	BO - Biophysics
R&D Projects	LM2011029 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
	LM2011026 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
	LO1309 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
Institutional support	FZU-D - RVO:68378271 ; UEM-P - RVO:68378041
UT WOS	000349611800083
EID SCOPUS	84923923585
DOI	10.1063/1.4907624
Annotation	Non-thermal plasmas hold great promise for a variety of biomedical applications. To ensure safe clinical application of plasma, a rigorous analysis of plasma-induced effects on cell functions is required. Yet mechanisms of bacteria deactivation by non-thermal plasma remain largely unknown. We therefore analyzed the influence of low-temperature atmospheric plasma on Gram-positive and Gram-negative bacteria. Using scanning electron microscopy, we demonstrate that both Gram-positive and Gram-negative bacteria strains in a minute were completely destroyed by helium plasma. In contrast, mesenchymal stem cells (MSCs) were not affected by the same treatment. Furthermore, histopathological analysis of hematoxylin and eosin–stained rat skin sections from plasma–treated animals did not reveal any abnormalities in comparison to control ones. We discuss possible physical mechanisms leading to the shred of bacteria under non-thermal plasma irradiation.
Workplace	Institute of Physics
Contact	Kristina Potocká, potocka@fzu.cz, Tel.: 220 318 579
Year of Publishing	2016

Number of the records: 1