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Iron oxides in human spleen
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SYSNO ASEP 0447822 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Iron oxides in human spleen Author(s) Kopáni, M. (SK)
Miglierini, M. (SK)
Lančok, Adriana (UACH-T) ORCID, RID, SAI
Dekan, J. (SK)
Čaplovicová, M. (SK)
Jakubovský, J. (SK)
Boča, R. (SK)
Mrazova, H. (SK)Source Title Biometals. - : Springer - ISSN 0966-0844
Roč. 28, č. 5 (2015), s. 913-928Number of pages 16 s. Language eng - English Country GB - United Kingdom Keywords diffraction ; iron ; magnetic properties Subject RIV CA - Inorganic Chemistry Institutional support UACH-T - RVO:61388980 UT WOS 000361430000011 EID SCOPUS 84941997595 DOI 10.1007/s10534-015-9876-2 Annotation Iron is an essential element for fundamental cell functions and a catalyst for chemical reactions. Three samples extracted from the human spleen were investigated by scanning (SEM) and transmission electron microscopy (TEM), Mossbauer spectrometry (MS), and SQUID magnetometry. The sample with diagnosis of hemosiderosis (H) differs from that referring to hereditary spherocytosis and the reference sample. SEM reveals iron-rich micrometer-sized aggregate of various structures-tiny fibrils in hereditary spherocytosis sample and no fibrils in hemochromatosis. Hematite and magnetite particles from 2 to 6mum in TEM with diffraction in all samples were shown. The SQUID magnetometry shows different amount of diamagnetic, paramagnetic and ferrimagnetic structures in the tissues. The MS results indicate contribution of ferromagnetically split sextets for all investigated samples. Their occurrence indicates that at least part of the sample is magnetically ordered below the critical temperature. The iron accumulation process is different in hereditary spherocytosis and hemosiderosis. This fact may be the reason of different iron crystallization. Workplace Institute of Inorganic Chemistry Contact Jana Kroneislová, krone@iic.cas.cz, Tel.: 311 236 931 Year of Publishing 2016
Number of the records: 1