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Development of Thermosensitive Hydrogels of Chitosan, Sodium and Magnesium Glycerophosphate for Bone Regeneration Applications
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SYSNO ASEP 0444730 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Development of Thermosensitive Hydrogels of Chitosan, Sodium and Magnesium Glycerophosphate for Bone Regeneration Applications Author(s) Lišková, Jana (FGU-C) RID, ORCID
Bačáková, Lucie (FGU-C) RID, ORCID
Skwarczyńska, A. L. (PL)
Musial, O. (BE)
Bliznuk, V. (BE)
De Schamphelaere, K. (BE)
Modrzejewska, Z. (PL)
Douglas, T.E.L. (BE)Source Title Journal of Functional Biomaterials. - : MDPI - ISSN 2079-4983
Roč. 6, č. 2 (2015), s. 192-203Number of pages 12 s. Language eng - English Country CH - Switzerland Keywords chitosan ; magnesium ; mineralization Subject RIV EI - Biotechnology ; Bionics OECD category Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions (pharmacogenomics, gene-based therapeutics) R&D Projects EE2.3.30.0025 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Institutional support FGU-C - RVO:67985823 UT WOS 000446636700003 DOI 10.3390/jfb6020192 Annotation Chitosan hydrogels could be formed by partial substitution of Na-beta-GP with Mg-GP at a molar ratio of 90:10. Gelation speeds were similar for chitosan/Na-beta-GP and chitosan/Na-beta-GP/Mg-GP hydrogels. Both hydrogel types were mineralized with apatite to a similar degree after incubation in SBF for 7 days. Both hydrogel types showed good and comparable cytocompatibility Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2016
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