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Solid-state NMR studies of nucleic acid components
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SYSNO ASEP 0443272 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Solid-state NMR studies of nucleic acid components Author(s) Dračínský, Martin (UOCHB-X) RID, ORCID
Hodgkinson, P. (GB)Number of authors 2 Source Title RSC Advances. - : Royal Society of Chemistry
Roč. 5, č. 16 (2015), s. 12300-12310Number of pages 11 s. Language eng - English Country GB - United Kingdom Keywords NMR spectroscopy ; nucleic acids ; solid-state NMR Subject RIV CB - Analytical Chemistry, Separation R&D Projects GA13-24880S GA ČR - Czech Science Foundation (CSF) Institutional support UOCHB-X - RVO:61388963 UT WOS 000348985400077 EID SCOPUS 84922267541 DOI 10.1039/c4ra14404j Annotation Recent applications of solid-state NMR to the characterisation of nucleic acid systems are reviewed. Developments in NMR methodology and DFT-based first-principles calculations have led to the emergence of "NMR crystallography", where solid-state NMR provides information on local structure and dynamics that complements information on periodic ordering and overall structure provided by traditional diffraction crystallography. The solid-state NMR is shown to provide direct information on hydrogen-bonding arrangements, metal ion interactions and local molecular dynamics that is difficult to obtain by other techniques, including solution-state NMR. Workplace Institute of Organic Chemistry and Biochemistry Contact asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434 Year of Publishing 2016 Electronic address http://pubs.rsc.org/en/content/articlepdf/2015/ra/c4ra14404j
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