Number of the records: 1

Tetracycline-inducible gene expression system in Leishmania mexicana

SYSNO ASEP	0439435
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Tetracycline-inducible gene expression system in Leishmania mexicana
Author(s)	Kraeva, N. (CZ) Ishemgulova, A. (CZ) Lukeš, Julius (BC-A)_{RID, ORCID} Yurchenko, Vyacheslav (BC-A)_{RID, ORCID}
Source Title	Molecular and Biochemical Parasitology. - : Elsevier - ISSN 0166-6851 Roč. 198, č. 1 (2014), s. 11-13
Number of pages	3 s.
Publication form	Print - P
Language	eng - English
Country	NL - Netherlands
Keywords	Leishmania mexicana ; Gene expression ; Tet-inducible system
Subject RIV	EB - Genetics ; Molecular Biology
R&D Projects	EE2.3.30.0032 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
Institutional support	BC-A - RVO:60077344
UT WOS	000347865800002
DOI	10.1016/j.molbiopara.2014.11.002
Annotation	Here we present a T7-driven, tetracycline-inducible system for protein expression in human pathogen Leishmania mexicana. The gene expression in this strain is tightly regulated and dose- and timedependent. This system can be widely used by the parasitology community to analyze effects of genes of interest on biology, physiology and virulence of parasites causing cutaneous leishmaniases.
Workplace	Biology Centre (since 2006)
Contact	Dana Hypšová, eje@eje.cz, Tel.: 387 775 214
Year of Publishing	2015

Number of the records: 1