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Proteomic Analysis of Human Tooth Pulp: Proteomics of Human Tooth
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SYSNO ASEP 0437660 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Proteomic Analysis of Human Tooth Pulp: Proteomics of Human Tooth Author(s) Eckhardt, Adam (FGU-C) RID, ORCID
Jágr, Michal (FGU-C) RID, ORCID
Pataridis, Statis (FGU-C)
Mikšík, Ivan (FGU-C) RID, ORCID, SAISource Title Journal of Endodontics. - : Elsevier - ISSN 0099-2399
Roč. 40, č. 12 (2014), s. 1961-1966Number of pages 6 s. Language eng - English Country US - United States Keywords dentin ; human pulp ; tandem mass spectrometry ; tooth proteome ; 2-dimensional gel electrophoresis Subject RIV FF - HEENT, Dentistry R&D Projects GA13-17224S GA ČR - Czech Science Foundation (CSF) GAP206/12/0453 GA ČR - Czech Science Foundation (CSF) NT14324 GA MZd - Ministry of Health (MZ) Institutional support FGU-C - RVO:67985823 UT WOS 000346553200012 EID SCOPUS 84908495569 DOI 10.1016/j.joen.2014.07.001 Annotation A total of 342 proteins were identified with high confidence, and 2 proteins were detected for the first time in an actual human sample. The identified tooth pulp proteins have a variety of functions: structural, catalytic, transporter, protease activity, immune response, and many others. In a comparison with dentin and blood plasma, 140 (pulp/dentin) shared proteins were identified, 37 of which were not observed in plasma. It can be suggested that they might participate in the unique pulp-dentin complex Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2015
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