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Mybs in mouse hair follicle development
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SYSNO ASEP 0436623 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Mybs in mouse hair follicle development Author(s) Veselá, Barbora (UZFG-Y) RID
Švandová, Eva (UZFG-Y) RID, ORCID
Šmarda, J. (CZ)
Matalová, Eva (UZFG-Y) RIDSource Title Tissue & Cell. - : Elsevier - ISSN 0040-8166
Roč. 46, č. 5 (2014), s. 352-355Number of pages 4 s. Publication form Print - P Language eng - English Country GB - United Kingdom Keywords hair follicle ; stem cells ; c-Myb ; B-Myb ; development Subject RIV EA - Cell Biology R&D Projects GCP302/12/J059 GA ČR - Czech Science Foundation (CSF) Institutional support UZFG-Y - RVO:67985904 UT WOS 000343808600009 EID SCOPUS 84908222939 DOI 10.1016/j.tice.2014.06.006 Annotation The Myb transcription factors are involved in essential cellular processes, such as cell proliferation, differentiation and cell death. Biological functions carried out by specific Myb proteins are distinct. Hair follicles are ectodermal-derived organs with cycling character of the growth resulting from the presence of somatic stem cells. In this study, we followed the expression of the Myb proteins in developing hair follicles and in the hair follicle stem cell niche by immunofluorescence staining. During hair follicle development, B-Myb was present in a few cells located in the area of cell division; c-Myb was abundant postanally in dividing cells but also in keratinizing zone. In addition, c-Myb was also detected in cells under the hair follicle bulge. These findings indicate possible involvement of c-Myb in regulation of activated stem cells leaving the niche. Workplace Institute of Animal Physiology and Genetics Contact Jana Zásmětová, knihovna@iapg.cas.cz, Tel.: 315 639 554 Year of Publishing 2015
Number of the records: 1