Number of the records: 1
Microsporum aenigmaticum sp nov from M. gypseum complex, isolated as a cause of tinea corporis
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SYSNO ASEP 0436029 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Microsporum aenigmaticum sp nov from M. gypseum complex, isolated as a cause of tinea corporis Author(s) Hubka, Vít (MBU-M) ORCID
Dobiášová, S. (CZ)
Dobiáš, R. (CZ)
Kolařík, Miroslav (MBU-M) RID, ORCIDSource Title Medical Mycology. - : Oxford University Press - ISSN 1369-3786
Roč. 52, č. 4 (2014), s. 387-396Number of pages 10 s. Language eng - English Country GB - United Kingdom Keywords Arthroderma ; geophilic dermatophytes ; keratinophilic fungi Subject RIV EE - Microbiology, Virology R&D Projects EE2.3.20.0055 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) EE2.3.30.0003 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Institutional support MBU-M - RVO:61388971 UT WOS 000339913600007 DOI 10.1093/mmy/myt033 Annotation An undescribed Microsporum species was isolated from skin scales recovered from a 40-mm large, annular, scaling lesion on the wrist of a 46-year-old woman. The risk factors for dermatophyte infection in the patient were frequent work in the garden, hunting, and contact with dogs and horses. Direct microscopic examination of the scales revealed the presence of dermatophyte hyphae; when the samples were cultured, a morphologically similar fungus grew on all slants in pure culture. Both of these findings strongly suggested that the isolate was the true causal agent of infection. The possible geophilic nature of the species was based on phylogenetic analysis (internal transcribed spacer region of rDNA and beta-tubulin gene) that placed it in between species of the M. gypseum complex. However, its divergencies from all other Microsporum species exceeded 4% base pairs. Based on beta-tubulin phylogeny, the isolated species is a sister to M. gypseum. The species produces abundant chlamydospores and clumps of hyphae similar to those of ascomatal primordia but no conidia and ascospores. The species was unable to grow at 37 degrees C and does not grow on T6 basal medium, which is unlike other Microsporum species; hair perforation and urease tests were positive. The addition of histidine to the T6 medium resulted in rapid growth of the fungus. The phylogenetic evidence, morphology, growth parameters, and physiology justified the proposal that the isolate is a new species, M. aenigmaticum, sp. nov. Workplace Institute of Microbiology Contact Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Year of Publishing 2015
Number of the records: 1