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Droplet microfluidics in (bio) chemical analysis

SYSNO ASEP	0434461
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Droplet microfluidics in (bio) chemical analysis
Author(s)	Basova, E. Y. (CZ) Foret, František (UIACH-O)_{RID, ORCID}
Number of authors	2
Source Title	Analyst. - : Royal Society of Chemistry - ISSN 0003-2654 Roč. 140, č. 1 (2015), s. 22-38
Number of pages	17 s.
Publication form	Print - P
Language	eng - English
Country	GB - United Kingdom
Keywords	droplet chemistry ; bioanalysis ; microfluidics ; protein
Subject RIV	CB - Analytical Chemistry, Separation
R&D Projects	GBP206/12/G014 GA ČR - Czech Science Foundation (CSF)
Institutional support	UIACH-O - RVO:68081715
UT WOS	000345824700003
DOI	10.1039/C4AN01209G
Annotation	Droplet microfluidics may soon change the paradigm of performing chemical analyses and related instrumentation. It is not only the analysis scale and possibility for sensitivity improvement, reduced consumption of chemical and biological reagents, but also the vast increase of the speed in performing a variety of unit operations. At present, microfluidic platforms can reproducibly generate monodisperse droplet populations at kHz or higher rate with droplet sizes suitable for high-throughput experiments, single-cell detection or even single molecule analysis. In addition to being used as microreactors with volume in the micro- to femtoliter range; droplet based systems have also been used to directly synthesize particles and encapsulate biological entities for biomedicine and biotechnology applications. This minireview summarizes the various droplet microfluidics operations and applications for (bio) chemical assays described in the literature during the past few years.
Workplace	Institute of Analytical Chemistry
Contact	Iveta Drobníková, drobnikova@iach.cz, Tel.: 532 290 234
Year of Publishing	2015

Number of the records: 1