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Development of radiometric assays for quantification of enzyme activities of the key enzymes of thyroid hormones metabolism
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SYSNO ASEP 0431267 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Development of radiometric assays for quantification of enzyme activities of the key enzymes of thyroid hormones metabolism Author(s) Pavelka, Stanislav (FGU-C) RID Source Title Physiological Research. - : Fyziologický ústav AV ČR, v. v. i. - ISSN 0862-8408
Roč. 63, Suppl.1 (2014), S133-S140Number of pages 8 s. Language eng - English Country CZ - Czech Republic Keywords enzyme ; metabolism ; radiometric assay ; thyroid hormone Subject RIV FB - Endocrinology, Diabetology, Metabolism, Nutrition R&D Projects 7AMB12SK158 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) GA304/08/0256 GA ČR - Czech Science Foundation (CSF) Institutional support FGU-C - RVO:67985823 UT WOS 000332073100011 EID SCOPUS 84897625884 Annotation We newly elaborated and adapted several radiometric enzyme assays for the determination of activities of the key enzymes engaged in the biosynthesis and metabolic transformations of thyroid hormones (THs) in the thyroid gland and in peripheral tissues, especially in white adipose tissue. These radiometric assays proved to be very useful tools for studies of factors modulating THs metabolism, not only in model animals but also in clinical studies of human obesity Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2015
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