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Handbook of Proteolytic Enzymes
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SYSNO ASEP 0425068 Document Type M - Monograph Chapter R&D Document Type Monograph Chapter Title Cathepsin D Author(s) Fusek, M. (CZ)
Mareš, Michael (UOCHB-X) RID, ORCID
Větvička, V. (US)Number of authors 3 Source Title Handbook of Proteolytic Enzymes. - Amsterdam : Academic Press, 2013 / Rawlings N. D. ; Salvesen G. - ISBN 978-0-12-382219-2 Pages s. 54-63 Number of pages 10 s. Number of pages 4104 Publication form Print - P Language eng - English Country GB - United Kingdom Keywords cathepsin D ; protease ; aspartic peptidase ; apoptosis ; cancer Subject RIV CE - Biochemistry R&D Projects IAA400550705 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) Institutional support UOCHB-X - RVO:61388963 UT WOS 000328545100010 EID SCOPUS 84884838168 DOI 10.1016/B978-0-12-382219-2.00008-9 Annotation The review provides an update on cathepsin D, an aspartic peptidase involved in a number of physiological and pathophysiological processes, including apoptosis, neurodegeneration, cancer progression and metastasis. The review covers the biochemical activity, structure and biological aspects of cathepsin D as well as its preparation and assay methods. Workplace Institute of Organic Chemistry and Biochemistry Contact asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434 Year of Publishing 2014
Number of the records: 1