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Sequential Shh expression in the development of the mouse upper functional incisor
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SYSNO ASEP 0397915 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Sequential Shh expression in the development of the mouse upper functional incisor Author(s) Hovořáková, Mária (UEM-P) RID
Smrčková, Lucie (UEM-P)
Lesot, H. (FR)
Lochovská, Kateřina (UEM-P)
Peterka, Miroslav (UEM-P) RID
Peterková, Renata (UEM-P) RIDNumber of authors 6 Source Title Journal of Experimental Zoology Part B: Molecular and Developmental Evolution Additional Title Information. - : Wiley - ISSN 1552-5007
Roč. 320, č. 7 (2013), s. 455-464Number of pages 10 s. Language eng - English Country US - United States Keywords mouse ; craniofacial ; ED13.5 Subject RIV EB - Genetics ; Molecular Biology R&D Projects GA304/09/1579 GA ČR - Czech Science Foundation (CSF) GAP305/12/1766 GA ČR - Czech Science Foundation (CSF) Institutional support UEM-P - RVO:68378041 UT WOS 000325473100006 EID SCOPUS 84885480743 DOI 10.1002/jez.b.22522 Annotation This study brings new insights into the early development of the upper incisor in mice and completes the data on normal mouse incisor development. The temporal-spatial pattern of Shh expression reflects the development of two tooth generations, being detectable in two successive, antero-posteriorly located areas in the prospective incisor region in the upper jaw. The first, anterior and superficial Shh expression domain reflects the rudimentary tooth development suppressed during evolution. Only the subsequent, posterior and deeper Shh expression region, appearing at ED13.5, correlates with the prospective upper functional incisor in wild-type mice. Workplace Institute of Experimental Medicine Contact Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Year of Publishing 2014
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