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Time-regulated drug delivery system based on coaxially incorporated platelet alpha-granules for biomedical use
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SYSNO ASEP 0397661 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Time-regulated drug delivery system based on coaxially incorporated platelet alpha-granules for biomedical use Author(s) Buzgo, Matej (UEM-P)
Jakubová, Radka (UEM-P)
Míčková, Andrea (UEM-P)
Rampichová, Michala (UEM-P) RID, ORCID
Prosecká, Eva (UEM-P)
Kochová, P. (CZ)
Lukáš, D. (CZ)
Amler, Evžen (UEM-P) RIDNumber of authors 8 Source Title Nanomedicine. - : Future Medicine - ISSN 1743-5889
Roč. 8, č. 7 (2013), s. 1137-1154Number of pages 18 s. Language eng - English Country GB - United Kingdom Keywords Core-shell nanofibers ; alpha granules ; cartilage tissue engineering Subject RIV FP - Other Medical Disciplines R&D Projects GAP304/10/1307 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50390703 - UEM-P (2007-2013) AV0Z50390512 - UEM-P (2005-2011) UT WOS 000320853500017 EID SCOPUS 84879663846 DOI 10.2217/NNM.12.140 Annotation Alpha granules are novel source of natural growth factors from platelets. In recent work we had sucesfully embedded alpha granules into nanofibers with core/shell structure. The alpha granules survived the electrospinning proces and growth factors retained their bioaktivity as was demonstarted on the model of chondrocytes and mesenchymal stem cells. Workplace Institute of Experimental Medicine Contact Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Year of Publishing 2014
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