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Microfluidic isotachophoresis: A review
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SYSNO ASEP 0395826 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Microfluidic isotachophoresis: A review Author(s) Smejkal, P. (AU)
Bottenus, D. (US)
Breadmore, M. C. (AU)
Guijt, R. M. (AU)
Ivory, C. F. (US)
Foret, František (UIACH-O) RID, ORCID
Macka, M. (AU)Number of authors 7 Source Title Electrophoresis. - : Wiley - ISSN 0173-0835
Roč. 34, č. 11 (2013), s. 1493-1509Number of pages 17 s. Publication form Print - P Language eng - English Country DE - Germany Keywords chip ; isotachophoresis ; microfluidics ; miniaturization Subject RIV CB - Analytical Chemistry, Separation R&D Projects GAP301/11/2055 GA ČR - Czech Science Foundation (CSF) Institutional support UIACH-O - RVO:68081715 UT WOS 000319939300001 DOI 10.1002/elps.201300021 Annotation Electromigration methods including CE and ITP are attractive for incorporation in microfluidic devices because they are relatively easily adaptable to miniaturization. After its popularity in the 1970s, ITP has made a comeback in microfluidic format (-ITP, micro-ITP) driven by the advantages of the steady-state boundary, the self-focusing effect, and the ability to aid in preconcentrating analytes in the sample while removing matrix components. In this review, we provide an overview of the developments in the area of -ITP in a context of the historic developments with a focus on recent developments in experimental and computational ITP and discuss possible future trends. The chip-ITP areas and topics discussed in this review and the corresponding sections include: PC simulations and modeling, analytical -ITP, preconcentration ITP, transient ITP, peak mode ITP, gradient elution ITP, and free-flow ITP, while the conclusions provide a critical summary and outlook. The review also contains experimental conditions for -ITP applications to real-world samples from over 50 original journal publications. Workplace Institute of Analytical Chemistry Contact Iveta Drobníková, drobnikova@iach.cz, Tel.: 532 290 234 Year of Publishing 2014
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