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Potentiation of Inhibitory Synaptic Transmission by Extracellular ATP in Rat Suprachiasmatic Nuclei

SYSNO ASEP	0392575
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Potentiation of Inhibitory Synaptic Transmission by Extracellular ATP in Rat Suprachiasmatic Nuclei
Author(s)	Bhattacharya, Anirban (FGU-C)_{RID, ORCID, SAI} Vávra, Vojtěch (FGU-C)_RID Svobodová, Irena (FGU-C)_{RID, ORCID} Bendová, Z. (CZ) Vereb, G. (HU) Zemková, Hana (FGU-C)_{RID, ORCID}
Source Title	Journal of Neuroscience. - : Society for Neuroscience - ISSN 0270-6474 Roč. 33, č. 18 (2013), s. 8035-8044
Number of pages	11 s.
Language	eng - English
Country	US - United States
Keywords	suprachiasmatic nucleus ; P2X receptors ; P2Y receptors ; ATP ; GABA ; spontaneous inhibitory synaptic currents
Subject RIV	ED - Physiology
R&D Projects	IAA500110910 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
	GBP304/12/G069 GA ČR - Czech Science Foundation (CSF)
	EE2.3.30.0025 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
Institutional support	FGU-C - RVO:67985823
UT WOS	000318420400039
EID SCOPUS	84877117298
DOI	10.1523/JNEUROSCI.4682-12.2013
Annotation	The hypothalamic suprachiasmatic nuclei (SCN), the circadian master clock in mammals, releases ATP in a rhythm. In this study, we examined the expression and function of ATP-gated P2X receptors (P2XRs) in the SCN neurons of rat brain slices. Our data show that ATP activates presynaptic P2X2Rs to regulate inhibitory synaptic transmission within the SCN and that this effect varies between dorsomedial and ventrilateral SCN regions
Workplace	Institute of Physiology
Contact	Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400
Year of Publishing	2014

Number of the records: 1