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Allergic sensitization to ovalbumin in mouse model of food allergy is accompanied by stimulation of enterocyte brush border alkaline phosphatase activity

SYSNO ASEP	0390888
Document Type	A - Abstract
R&D Document Type	The record was not marked in the RIV
R&D Document Type	Není vybrán druh dokumentu
Title	Allergic sensitization to ovalbumin in mouse model of food allergy is accompanied by stimulation of enterocyte brush border alkaline phosphatase activity
Author(s)	Schwarzer, Martin (MBU-M)_{ORCID, RID} Kozáková, Hana (MBU-M)_{RID, ORCID} Goliáš, Jaroslav (MBU-M)_RID Kverka, Miloslav (MBU-M)_{RID, ORCID} Cinová, Jana (MBU-M) Rossmann, Pavel (MBU-M) Tučková, Ludmila (MBU-M)_RID
Source Title	Genes and Nutrition - ISSN 1555-8932 Roč. 6, č. 1 (2012), s. 53-53
Number of pages	1 s.
Action	Meeting of the European Intestinal Transport Group /24./
Event date	04.09.2012-07.09.2012
VEvent location	Oxford
Country	GB - United Kingdom
Event type	EUR
Language	eng - English
Country	US - United States
Keywords	ovalbumin ; allergy
Subject RIV	EC - Immunology
R&D Projects	IAA500200913 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
CEZ	AV0Z50200510 - MBU-M (2005-2011)
Annotation	The main egg protein ovalbumin (OVA) belongs to the six most frequent food allergens and its allergenicity is intensively studied in an experimental models. Aim In our study we focused not only on immune responses but also on changes in allergenicity of ovalbumin after the thermal treatment in mouse model of Type I food allergy. We observed that allergic response in experimental model of food allergy to OVA is strongly influenced by its thermal processing and that activity of jejunal alkaline phosphatase has a pivotal role in intestinal homeostasis
Workplace	Institute of Microbiology
Contact	Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231
Year of Publishing	2013

Number of the records: 1