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Pyrazolo[4,3-D]pyrimidines, process for their preparation and methods of use
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SYSNO ASEP 0380690 Document Type P - Patent R&D Document Type Patent or other outcome protected by special legislation Title Pyrazolo[4,3-D]pyrimidines, process for their preparation and methods of use Author(s) Moravcová, Daniela (UEB-Q)
Havlíček, Libor (UEB-Q) RID, ORCID
Kryštof, Vladimír (UEB-Q) RID, ORCID
Lenobel, René (UEB-Q) ORCID
Binarová, Pavla (UEB-Q) RID
Mlejnek, P. (CZ)
Vojtěšek, B. (CZ)
Uldrijan, S. (CZ)
Schmülling, T. (DE)
Strnad, Miroslav (UEB-Q) RID, ORCIDYear of issue 2012 Possible third party use of the result A - Pro využití výsledku jiným subjektem je vždy nutné nabytí licence Royalty requested A - Poskytovatel licence požaduje licenční poplatek Patent no. or utility model no. or industrial design no. CA2524344 Date of the patent acceptance 13.03.2012 Name of the patent owner Ústav experimentální botaniky AV ČR, v. v. i - Univerzita Palackého v Olomouci Code of the issuer name CA001 - Canadian Intellectual Property Office (CIPO) Gatineau, Québec Current use B - Patent je využíván na základě uzavřené licenční smlouvy mezi vlastníkem a uživatelem Language eng - English Keywords Pyrazolo[4,3-D]pyrimidines ; preparation ; methods of use Subject RIV CE - Biochemistry CEZ AV0Z50380511 - UEB-Q (2005-2011) Annotation The invention relates to 3-, 7-disubstituted pyrazolo[4,3-d]pyrimidines represented by the general formula I (I), and pharmaceutically acceptable salts thereof, wherein R3 is selected from the group consisting of alkyl, cycloalkyl, , cycloalkyl alkyl, cycloheteroalkyl alkyl, cycloheteroalkyl, aryl, heterocycle, heteroaryl, arylalkyl, heteroarylalkyl, and heteroalkyl, wherein each of the groups may optionally be substituted, R7 is selected from the group consisting of halogen, hydroxyl, hydroxylamino, amino, carboxyl, cyano, nitro, amido, sulfo, sulfamido, carbamino, unsubstituted or substituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted arylalkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted heteroarylakyl, substituted or unsubstituted cycloalkyl alkyl, substituted or unsubstituted cycloheteroalkyl alkyl; R7'-X- wherein X is an - NH-, -N(alkyl)-, -0- or -S- moiety and R7' is selected from the group consisting of H, alkyl, cycloalkyl, aryl, alkylcycloalkyl, arylalkyl, heterocycle, heterocyclealkyl, substituted alkyl, substituted cycloalkyl, substituted aryl, substituted arylalkyl, substituted heterocycle, substituted heteroaryl, substituted heteroarylalkyl, substituted heteroalkyl, substituted cycloalkyl alkyl and substituted cycloheteroalkyl alkyl, wherein the groups are preferably substituted by more than one halogen, hydroxyl, amino, mercapto, carboxyl, cyano, nitro, amido, sulfo, sulfamido, carbamino, alkyl, alkoxy, and substituted alkyl group. Workplace Institute of Experimental Botany Contact David Klier, knihovna@ueb.cas.cz, Tel.: 220 390 469 Year of Publishing 2013 Electronic address http://brevets-patents.ic.gc.ca/opic-cipo/cpd/eng/patent/2524344/summary.html
Number of the records: 1