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Immunochemical detection of oxidatively damaged DNA

SYSNO ASEP	0377754
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Immunochemical detection of oxidatively damaged DNA
Author(s)	Rössner ml., Pavel (UEM-P)_{RID, ORCID} Šrám, Radim (UEM-P)_RID
Source Title	Free Radical Research. - : Taylor & Francis - ISSN 1071-5762 Roč. 46, č. 4 (2012), s. 492-522
Number of pages	31 s.
Language	eng - English
Country	GB - United Kingdom
Keywords	oxidative DNA damage ; ELISA ; immunohistochemistry
Subject RIV	DN - Health Impact of the Environment Quality
R&D Projects	SP/1B3/50/07 GA MŽP - Ministry of Environment (MŽP)
	2B08005 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
	GAP503/11/0084 GA ČR - Czech Science Foundation (CSF)
Institutional support	UEM-P - RVO:68378041
CEZ	AV0Z50390703 - UEM-P (2007-2013)
UT WOS	000301458200008
EID SCOPUS	84858136233
DOI	10.3109/10715762.2011.632415
Annotation	Several methods have been developed to detect oxidatively damaged DNA. This review evaluates the studies dealing with the detection of 8-oxodG in humans, the most abundant oxidized nucleoside. Authors concentrated especially on studies which used enzyme linked immunosorbent assay and immunohistochemistry to detect 8-oxodG in humans, laboratory animals and in cell lines. Oxidative damage observed in these organisms resulted from disease, exposure to environmental pollutants of from in vitro treatment with various chemical and physical factors.
Workplace	Institute of Experimental Medicine
Contact	Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218
Year of Publishing	2013

Number of the records: 1