Number of the records: 1
Immunochemical detection of oxidatively damaged DNA
- 1.
SYSNO ASEP 0377754 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Immunochemical detection of oxidatively damaged DNA Author(s) Rössner ml., Pavel (UEM-P) RID, ORCID
Šrám, Radim (UEM-P) RIDSource Title Free Radical Research. - : Taylor & Francis - ISSN 1071-5762
Roč. 46, č. 4 (2012), s. 492-522Number of pages 31 s. Language eng - English Country GB - United Kingdom Keywords oxidative DNA damage ; ELISA ; immunohistochemistry Subject RIV DN - Health Impact of the Environment Quality R&D Projects SP/1B3/50/07 GA MŽP - Ministry of Environment (MŽP) 2B08005 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) GAP503/11/0084 GA ČR - Czech Science Foundation (CSF) Institutional support UEM-P - RVO:68378041 CEZ AV0Z50390703 - UEM-P (2007-2013) UT WOS 000301458200008 EID SCOPUS 84858136233 DOI 10.3109/10715762.2011.632415 Annotation Several methods have been developed to detect oxidatively damaged DNA. This review evaluates the studies dealing with the detection of 8-oxodG in humans, the most abundant oxidized nucleoside. Authors concentrated especially on studies which used enzyme linked immunosorbent assay and immunohistochemistry to detect 8-oxodG in humans, laboratory animals and in cell lines. Oxidative damage observed in these organisms resulted from disease, exposure to environmental pollutants of from in vitro treatment with various chemical and physical factors. Workplace Institute of Experimental Medicine Contact Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Year of Publishing 2013
Number of the records: 1