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Superparamagnitnye nanochastitsy na osnove oksidov zheleza s modifitsirovannoj poverkhnostyu, sposob ikh polucheniya i primenenie
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SYSNO ASEP 0373388 Document Type P - Patent R&D Document Type Patent or other outcome protected by special legislation Title Superparamagnitnye nanochastitsy na osnove oksidov zheleza s modifitsirovannoj poverkhnostyu, sposob ikh polucheniya i primenenie Title Iron oxide-based superparamagnetic nanoparticles with modified surface, process of their preparation and use Author(s) Horák, Daniel (UMCH-V) RID, ORCID
Syková, Eva (UEM-P) RID
Babič, Michal (UMCH-V) RID, ORCID
Jendelová, Pavla (UEM-P) RID, ORCID
Hájek, Milan (UEM-P)Year of issue 2011 Possible third party use of the result A - Pro využití výsledku jiným subjektem je vždy nutné nabytí licence Royalty requested A - Poskytovatel licence požaduje licenční poplatek Patent no. or utility model no. or industrial design no. EA015718 Date of the patent acceptance 31.10.2011 Name of the patent owner Ústav makromolekulární chemie AV ČR, v. v. i. - Ústav experimentální medicíny AV ČR, v. v. i Code of the issuer name EAPO1 - The Eurasian Patent Organization Current use A - Pouze udělený (dosud nevyužívaný) patent nebo patent využívaný jeho vlastníkem Language rus - Russian Keywords superparamagnetic ; nanoparticles ; cell labeling Subject RIV CD - Macromolecular Chemistry R&D Projects GA203/09/1242 GA ČR - Czech Science Foundation (CSF) 1M0538 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z40500505 - UMCH-V (2005-2011) AV0Z50390512 - UEM-P (2005-2011) Annotation V nastoyashchyee izobretenie raskryvaetsya superparamagnitnykh nanochastits zondov na osnove oksidov zheleza, predpochtitelno magnetita ili maggemita s modifitsirovannoj poverkhnostyu , otlichayushchijsya tem, chto oni pokryty s mono -, di- ili polisakharidov vybran iz gruppy, sostoyashchyej iz D- arabinozy, D- glyukozy , D- galaktozy , D- mannozy, laktozy, maltozy, dekstranov i dekstrinov ili aminokislot ili poli ( aminokisloty) s iz gruppy, vklyuchayushchyej alanin , glitsin, glutamin , asparagin, gistidin, arginin , L lizina , asparaginovoj i glutaminovoj kisloty i obrazuyut kolloidnyj , sostoyashchij iz chastits. Description in English In the present invention, there are disclosed superparamagnetic nanoparticle probes based on iron oxides, preferably magnetite or maghemite, with modified surface, characterized in that they are coated with mono-, di- or polysaccharides being selected from the group consisting of D-arabinose, D-glucose, D-galactose, D-mannose, lactose, maltose, dextrans and dextrins or amino acids or poly(amino acid)s from the group including alanine, glycine, glutamine, asparagine, histidine, arginine, L lysine, aspartic and glutamic acid, and form a colloid consisting of particles. Workplace Institute of Macromolecular Chemistry Contact Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358 Year of Publishing 2012 Electronic address http://www.eapatis.com/ruSearch/ms.exeData/EAPO/EAPO2011/PDF/015718.PDF
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