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Aging and longevity of yeast colony populations: metabolic adaptation and differentiation
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SYSNO ASEP 0370714 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Aging and longevity of yeast colony populations: metabolic adaptation and differentiation Author(s) Váchová, Libuše (MBU-M) RID, ORCID
Palková, Z. (CZ)Source Title Biochemical Society Transactions. - : Portland Press - ISSN 0300-5127
Roč. 39, - (2011), s. 1471-1475Number of pages 5 s. Language eng - English Country GB - United Kingdom Keywords adaptation and longevity ; ammonia signalling ; quorum sensing Subject RIV EE - Microbiology, Virology R&D Projects GA204/08/0718 GA ČR - Czech Science Foundation (CSF) LC531 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z50200510 - MBU-M (2005-2011) UT WOS 000295745200063 DOI 10.1042/BST0391471 Annotation Yeast multicellular colonies possess several traits that are absent from individual yeasts. These include the ability to synchronize colony population development and adapt its metabolism to different environmental changes, such as nutrient depletion. This, together with cell diversification to cell variants with distinct metabolic and other properties, contributes to the main goal of the colony population: to achieve longevity. In this respect, a benefit to individual cells is subordinated to the benefit to the whole population, exhibiting a kind of altruistic behaviour. For example, some colony cells located at particular positions undergo regulated cell dying and provide components to other cells located in more propitious areas. The enhancement of techniques that enable the in vivo investigation of three-dimensional spatiotemporal colony development can lead to new discoveries on metabolic differentiation and regulation in the near future Workplace Institute of Microbiology Contact Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Year of Publishing 2012
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