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The slower the better: how sperm capacitation and acrosome reaction is modified in the presence of estrogens

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    SYSNO ASEP0370076
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JČlánek ve WOS
    TitleThe slower the better: how sperm capacitation and acrosome reaction is modified in the presence of estrogens
    Author(s) Šebková, N. (CZ)
    Černá, M. (CZ)
    Děd, Lukáš (BTO-N) RID
    Pěknicová, Jana (BTO-N) RID
    Dvořáková-Hortová, K. (CZ)
    Number of authors5
    Source TitleReproduction - ISSN 1470-1626
    Roč. 143, č. 3 (2012), s. 297-307
    Number of pages11 s.
    Languageeng - English
    CountryGB - United Kingdom
    Keywordssperm capacitation ; estrogen ; phosphorylation
    Subject RIVED - Physiology
    R&D Projects1M06011 GA MŠk - Ministry of Education, Youth and Sports (MEYS)
    CEZAV0Z50520701 - BTO-N (2007-2013)
    UT WOS000302920900006
    DOI10.1530/REP-11-0326
    AnnotationIt has been demonstrated that both natural and synthetical estrogens can modify the physiological progress of mouse sperm capacitation. The potential risk in the procapacitation effect of estrogens can also be seen in the decreased ability of sperm to undergo the acrosome reaction. In conclusion, the capacitating ability of sperm can be significantly lowered by increasing the level of estrogens in the environment.
    WorkplaceInstitute of Biotechnology
    ContactMonika Kopřivová, koprivom@img.cas.cz, Tel.: 296 443 610
    Year of Publishing2013