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Structural basis for DNA recognition by FOXO proteins
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SYSNO ASEP 0369959 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Structural basis for DNA recognition by FOXO proteins Author(s) Obšil, T. (CZ)
Obšilová, Veronika (FGU-C) RID, ORCID, SAISource Title Biochimica Et Biophysica Acta-Molecular Cell Research. - : Elsevier - ISSN 0167-4889
Roč. 1813, č. 11 (2011), s. 1946-1953Number of pages 8 s. Language eng - English Country NL - Netherlands Keywords forkhead ; FOXO ; DNA ; structure ; DNA recognition Subject RIV CE - Biochemistry R&D Projects IAA501110801 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) GAP207/11/0455 GA ČR - Czech Science Foundation (CSF) LC554 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z50110509 - FGU-C (2005-2011) UT WOS 000295766200004 DOI 10.1016/j.bbamcr.2010.11.025 Annotation The FOXO forkhead transcription factors are involved in metabolism control, cell survival, cellular proliferation DNA damage repair response, and stress resistance. The aim of this review is to summarize the recent structural characterization of FOXO proteins, the mechanisms of DNA recognition and the role of posttranslational modifications in the regulation of FOXO DNA-binding properties Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2012
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