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Modulation of gap-junctional intercellular communication by a series of cyanobacterial samples from nature and laboratory cultures
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SYSNO ASEP 0369524 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Modulation of gap-junctional intercellular communication by a series of cyanobacterial samples from nature and laboratory cultures Author(s) Nováková, K. (CZ)
Babica, Pavel (BU-J) RID, ORCID
Adamovský, O. (CZ)
Bláha, Luděk (BU-J)Number of authors 4 Source Title Toxicon. - : Elsevier - ISSN 0041-0101
Roč. 58, č. 1 (2011), s. 76-84Number of pages 9 s. Language eng - English Country GB - United Kingdom Keywords cyanotoxins ; gap-junctional intercellular communication ; tumor promotion Subject RIV EF - Botanics R&D Projects GA524/08/0496 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z60050516 - BU-J (2005-2011) UT WOS 000294031000010 DOI 10.1016/j.toxicon.2011.05.006 Annotation Extracts and exudates of cyanobacteria inhibit gap-junctional intercellular communication in rat liver cells in vitro. Inhibitory effects on GJIC were caused by chemicals different from microcystin and cylindrospermopsin, which indicates an existence of novel tumor promoting cyanotoxins. The effects were induced by common bloom-forming cyanobacteria (Anabaena, Aphanizomenon, Microcystis, Planktothrix), but the inhibitory potencies of extrats and exudates were species- and strain-specific. Workplace Institute of Botany Contact Martina Bartošová, martina.bartosova@ibot.cas.cz, ibot@ibot.cas.cz, Tel.: 271 015 242 ; Marie Jakšová, marie.jaksova@ibot.cas.cz, Tel.: 384 721 156-8 Year of Publishing 2012
Number of the records: 1