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Effect of high phosphorus diet on tooth microstructure of rodent incisors
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SYSNO ASEP 0368271 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Effect of high phosphorus diet on tooth microstructure of rodent incisors Author(s) Jekl, V. (CZ)
Krejčířová, L. (CZ)
Buchtová, Marcela (UZFG-Y) RID, ORCID
Knotek, Z. (CZ)Number of authors 4 Source Title Bone. - : Elsevier - ISSN 8756-3282
Roč. 49, č. 3 (2011), s. 479-484Number of pages 6 s. Language eng - English Country US - United States Keywords Enamel ; Hypoplasia ; Dentin Subject RIV FF - HEENT, Dentistry CEZ AV0Z50450515 - UZFG-Y (2005-2011) UT WOS 000293805100020 DOI 10.1016/j.bone.2011.04.021 Annotation Enamel hypoplasia and disruption of dentinogenesis are the most common abnormalities of development and mineralization of human teeth. Several reports are available in the literature on the influence of dietary calcium on the formation of human and rodent tooth; however, the information about the influence of dietary phosphorus on the tooth formation is scarce. The aim of the present investigation was to examine the chronic effect of high phosphorus diet and improper dietary calcium to phosphorus ratio on the mandibular incisor microstructure in a hystricomorph rodent - Octodon degu - using macroscopic observation, histopathological examination, transmission and scanning electron microscopy. The present study shows that enamel and dentin development is disturbed under high phosphorus diet and improper calcium to phosphorus ratio. Disturbed mineral metabolism resulted in enamel depigmentation, enamel hypoplasia, enamel pitting and altered dentin morphology. Workplace Institute of Animal Physiology and Genetics Contact Jana Zásmětová, knihovna@iapg.cas.cz, Tel.: 315 639 554 Year of Publishing 2012
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