Number of the records: 1

Nucleobase modification as redox DNA labelling for electrochemical detection

SYSNO ASEP	0368112
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Nucleobase modification as redox DNA labelling for electrochemical detection
Author(s)	Hocek, Michal (UOCHB-X)_{RID, ORCID} Fojta, Miroslav (BFU-R)_{RID, ORCID}
Number of authors	2
Source Title	Chemical Society Reviews. - : Royal Society of Chemistry - ISSN 0306-0012 Roč. 40, č. 12 (2011), s. 5802-5814
Number of pages	13 s.
Language	eng - English
Country	GB - United Kingdom
Keywords	nucleotides ; oligonucleotides ; DNA ; electrochemistry ; redox labeling
Subject RIV	CC - Organic Chemistry
R&D Projects	LC06035 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
	LC512 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
	IAA400040901 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
	GA203/09/0317 GA ČR - Czech Science Foundation (CSF)
CEZ	AV0Z40550506 - UOCHB-X (2005-2011)
	AV0Z50040507 - BFU-R (2005-2011)
	AV0Z50040702 - BFU-R (2007-2013)
UT WOS	000296986000016
DOI	10.1039/c1cs15049a
Annotation	Basic aspects of DNA electrochemistry with a strong focus on the use of modified nucleobases as redox probes for electrochemical bioanalysis are reviewed. Intrinsic electrochemical properties of nucleobases in combination with artificial redox-active nucleobase modifications are frequently applied in this field. Synthetic approaches to base-modified nucleic acids are briefly summarized and their applications in redox labelling are discussed.
Workplace	Institute of Organic Chemistry and Biochemistry
Contact	asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434
Year of Publishing	2012

Number of the records: 1