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Cancer physics: diagnostics based on damped cellular elastoelectrical vibrations in microtubules
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SYSNO ASEP 0368053 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Cancer physics: diagnostics based on damped cellular elastoelectrical vibrations in microtubules Author(s) Pokorný, Jiří (URE-Y) RID
Vedruccio, C. (IT)
Cifra, Michal (URE-Y) RID, ORCID, SAI
Kučera, Ondřej (URE-Y) RIDNumber of authors 4 Source Title European Biophysics Journal With Biophysics Letters - ISSN 0175-7571
Roč. 40, č. 6 (2011), s. 747-759Number of pages 13 s. Language eng - English Country DE - Germany Keywords cancer ; cellular biophysics ; bioelectric phenomena Subject RIV JA - Electronics ; Optoelectronics, Electrical Engineering R&D Projects GAP102/11/0649 GA ČR - Czech Science Foundation (CSF) GPP102/10/P454 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z20670512 - URE-Y (2005-2011) UT WOS 000290331400005 DOI 10.1007/s00249-011-0688-1 Annotation This paper describes a proposed biophysical mechanism of a novel diagnostic method for cancer developed recently by Vedruccio. The diagnostic method is based on frequency selective absorption of electromagnetic waves by malignant tumors. From physical point of view, cancer is connected with disrupted mitochondrial function. We argue in this paper that this leads to lowered ordering level of cellular water, and increased damping of microtubule based cellular elasto-electrical vibration states. These changes manifest as a dip of the amplitude at the fundamental frequency of the signal which is generated by a non linear microwave oscillator, the core of the diagnostic device, when coupled to the investigated cancerous tissue via the near-field. The dip is not present in the case of healthy tissue. Workplace Institute of Radio Engineering and Electronics Contact Petr Vacek, vacek@ufe.cz, Tel.: 266 773 413, 266 773 438, 266 773 488 Year of Publishing 2012
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