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REVIEWS IN FLUORESCENCE 2009

SYSNO ASEP	0367726
Document Type	M - Monograph Chapter
R&D Document Type	Monograph Chapter
Title	Z-Scan Fluorescence Correlation Spectroscopy: A Powerful Tool for Determination of Lateral Diffusion in Biological Systems
Author(s)	Štefl, Martin (UFCH-W) Macháň, Radek (UFCH-W) Hof, Martin (UFCH-W)_{RID, ORCID}
Source Title	REVIEWS IN FLUORESCENCE 2009. - New York : KLUWER ACADEMIC/PLENUM PUBL, 2011 / Geddes C. D. - ISSN 1573-8086 - ISBN 978-1-4419-9671-8
Pages	s. 321-344
Number of pages	24 s.
Number of pages	389
Language	eng - English
Country	US - United States
Keywords	image correlation spectroscopy ; single particle tracking ; spectroscopy
Subject RIV	CF - Physical ; Theoretical Chemistry
R&D Projects	GAP208/10/1090 GA ČR - Czech Science Foundation (CSF)
	GAP208/10/0376 GA ČR - Czech Science Foundation (CSF)
CEZ	AV0Z40400503 - UFCH-W (2005-2011)
UT WOS	000294140400012
DOI	10.1007/978-1-4419-9672-5
Annotation	The characterization of the dynamics of biological membranes is a topic which currently grasps a high level of attention. Biological membranes are extremely important as they are required for both protection and communication of eukaryotic cells. They also play a key role for transportation of nutrients into and out of the cell. Recent studies have proved that biological membranes are not homogeneous but are instead composed of microdomains, which complicate the precise determination of lateral diffusion coefficients. Z-scan fluorescence correlation spectroscopy (Z-scan FCS), one of the fluorescence fluctuation methods, is a technique which can be employed to determine lateral diffusion coefficients of membrane lipids and also membrane-associated molecules. Moreover, when Z-scan FCS is used in combination with Wawrezinieck diffusion law, lipid rafts in heterogeneous membranes can be monitored.
Workplace	J. Heyrovsky Institute of Physical Chemistry
Contact	Michaela Knapová, michaela.knapova@jh-inst.cas.cz, Tel.: 266 053 196
Year of Publishing	2012

Number of the records: 1