Number of the records: 1  

Biomaterials Applications for Nanomedicine

  1. 1.
    SYSNO ASEP0367638
    Document TypeM - Monograph Chapter
    R&D Document TypeMonograph Chapter
    TitleHydrogel Scaffolds Contribute to the Ostogenesis and Chondrogenesis in the Small Osteochongral Defects
    Author(s) Petrtýl, M. (CZ)
    Lísal, J. (CZ)
    Šenolt, L. (CZ)
    Bastl, Zdeněk (UFCH-W) RID, ORCID
    Kruliš, Zdeněk (UMCH-V) RID, ORCID
    Polanská, M. (CZ)
    Hulejová, H. (CZ)
    Černý, P. (CZ)
    Danešová, J. (CZ)
    Source TitleBiomaterials Applications for Nanomedicine. - Rijeka : InTech, 2011 / Pignatello R. - ISBN 978-953-307-661-4
    Pagess. 53-68
    Number of pages16 s.
    Number of pages458
    Languageeng - English
    CountryHR - Croatia
    Keywordsosteogenesis ; chondrogenesis ; physical chemistry
    Subject RIVCF - Physical ; Theoretical Chemistry
    R&D ProjectsGA106/06/0761 GA ČR - Czech Science Foundation (CSF)
    CEZAV0Z40400503 - UFCH-W (2005-2011)
    AV0Z40500505 - UMCH-V (2005-2011)
    AnnotationHyaline cartilage shows only a limited response to self-repair (Hunter, 1743). Many people are stricken with degenerative osteochondral defects. Modern therapies of osteochondral defects are focused (for example) on the transplantation of osteochondral autografts, rushed spongiosa with collagen, chondrocytes and many others. The insertion of a crushed autologous bone graft has been reported as a possible therapy. However, the regenerative biomechanical (material) quality was less than 70% of healthy cartilage for fragments and controls (Kleemann et al., 2006). The transplantation of autologous osteochondral 3Dcylinders is one of several surgical therapies (Horas, 2003). During operations osteochondral defects are filled with material of a natural histological structure.
    WorkplaceJ. Heyrovsky Institute of Physical Chemistry
    ContactMichaela Knapová, michaela.knapova@jh-inst.cas.cz, Tel.: 266 053 196
    Year of Publishing2012
Number of the records: 1  

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