Number of the records: 1

Phylogeny, longevity and evolution of adaptive immunity

SYSNO ASEP	0367535
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Phylogeny, longevity and evolution of adaptive immunity
Author(s)	Vinkler, Michal (UBO-W)_{RID, ORCID} Albrecht, Tomáš (UBO-W)_{RID, SAI, ORCID}
Number of authors	2
Source Title	Folia zoologica. - : Ústav biologie obratlovců AV ČR, v. v. i. - ISSN 0139-7893 Roč. 60, č. 3 (2011), s. 277-282
Number of pages	6 s.
Language	eng - English
Country	CZ - Czech Republic
Keywords	acquired immunity ; evolutionary immunology ; immunological priming ; innate immunity ; invertebrates
Subject RIV	EG - Zoology
R&D Projects	GA206/08/0640 GA ČR - Czech Science Foundation (CSF)
	GA206/08/1281 GA ČR - Czech Science Foundation (CSF)
	GAP505/10/1871 GA ČR - Czech Science Foundation (CSF)
CEZ	AV0Z60930519 - UBO-W (2005-2011)
UT WOS	000296301300011
EID SCOPUS	80053993764
Annotation	Adaptive immunity is commonly viewed as a unique vertebrate feature. A misleading view on vertebrate longevity compared to non-vertebrate animals together with oversimplification of 'invertebrate' phylogeny sometimes serves for justifying the limitation of adaptive immunity exclusively to vertebrates. However, here we emphasise that the borderline for differentiation between 'innate' and 'adaptive' immunity may be fuzzy and artificial. In invertebrates with a long lifespan some kind of acquired immunity could exist. We therefore stress that the definition of 'adaptivity' of immune response should reflect the system function instead of a certain molecular mechanism adopted. If these altered criteria are considered then several pieces of recent evidence indicate that the adaptive immunity in animals might have arisen several times independently and in very different forms.
Workplace	Institute of Vertebrate Biology
Contact	Hana Slabáková, slabakova@ivb.cz, Tel.: 543 422 524
Year of Publishing	2012

Number of the records: 1