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DNA Damage during G2 Phase Does Not Affect Cell Cycle Progression of the Green Alga Scenedesmus quadricauda
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SYSNO ASEP 0367294 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title DNA Damage during G2 Phase Does Not Affect Cell Cycle Progression of the Green Alga Scenedesmus quadricauda Author(s) Hlavová, Monika (MBU-M)
Čížková, Mária (MBU-M) ORCID
Vítová, Milada (MBU-M) RID, ORCID
Bišová, Kateřina (MBU-M) RID
Zachleder, Vilém (MBU-M) ORCIDSource Title PLoS ONE. - : Public Library of Science - ISSN 1932-6203
Roč. 6, č. 5 (2011), s. 1-13Number of pages 13 s. Language eng - English Country US - United States Keywords DOUBLE-STRAND BREAKS ; P53-DEPENDENT G(1) ARREST ; HISTONE H1 KINASE Subject RIV EE - Microbiology, Virology R&D Projects IAA500200614 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) GA204/09/0111 GA ČR - Czech Science Foundation (CSF) GA525/09/0102 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50200510 - MBU-M (2005-2011) UT WOS 000290656300015 DOI 10.1371/journal.pone.0019626 Annotation DNA damage is a threat to genomic integrity in all living organisms. Plants and green algae are particularly susceptible to DNA damage especially that caused by UV light, due to their light dependency for photosynthesis. For survival of a plant, and other eukaryotic cells, it is essential for an organism to continuously check the integrity of its genetic material and, when damaged, to repair it immediately. Cells therefore utilize a DNA damage response pathway that is responsible for sensing, reacting to and repairing damaged DNA. We have studied the effect of 5-fluorodeoxyuridine, zeocin, caffeine and combinations of these on the cell cycle of the green alga Scenedesmus quadricauda Workplace Institute of Microbiology Contact Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Year of Publishing 2012
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