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Molecular characterization of the iron binding protein ferritin in Eisenia andrei earthworms

SYSNO ASEP	0366799
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Molecular characterization of the iron binding protein ferritin in Eisenia andrei earthworms
Author(s)	Procházková, Petra (MBU-M)_{RID, ORCID} Dvořák, Jiří (MBU-M)_{RID, ORCID} Šilerová, Marcela (MBU-M) Roubalová, Radka (MBU-M)_{RID, ORCID} Škanta, František (MBU-M)_RID Halada, Petr (MBU-M)_{RID, ORCID} Bilej, Martin (MBU-M)_{RID, ORCID}
Source Title	Gene. - : Elsevier - ISSN 0378-1119 Roč. 485, č. 2 (2011), s. 73-80
Number of pages	8 s.
Language	eng - English
Country	NL - Netherlands
Keywords	Earthworms ; Invertebrates ; Ferritin
Subject RIV	EC - Immunology
R&D Projects	GA206/07/0378 GA ČR - Czech Science Foundation (CSF)
	GD310/08/H077 GA ČR - Czech Science Foundation (CSF)
	IAA600200704 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
	2B06155 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
	LC07017 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
CEZ	AV0Z50200510 - MBU-M (2005-2011)
UT WOS	000295069800003
DOI	10.1016/j.gene.2011.06.010
Annotation	Ferritin is a storage protein that plays a key role in iron metabolism. In this study, we report on the sequence characterization of a ferritin-coding cDNA in Eisenia andrei earthworms isolated by RT-PCR using degenerated primers, and we suggest the presence of a putative IRE in the 5′-UTR of ferritin mRNA. The obtained ferritin sequence was compared with those of other animals showing sequence and structure homology in consensus sites, including the iron-responsive element (IRE) and ferroxidase centers. Despite the sequence homology in the E. andrei mRNA of ferritin with the sequences of other animals in consensus IRE sites, the presented cytosine in the IRE of E. andrei ferritin in the expected position does not form a conventional bulge
Workplace	Institute of Microbiology
Contact	Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231
Year of Publishing	2012

Number of the records: 1