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Favorable effects of trehalose on the development of UVB-mediated antioxidant/prooxidant imbalance in the corneal epithelium, proinflammatory cytokine and matrix metalloproteinase induction, and heat shock protein 70 expression

  1. 1.
    SYSNO ASEP0366470
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JČlánek ve WOS
    TitleFavorable effects of trehalose on the development of UVB-mediated antioxidant/prooxidant imbalance in the corneal epithelium, proinflammatory cytokine and matrix metalloproteinase induction, and heat shock protein 70 expression
    Author(s) Čejková, Jitka (UEM-P) RID
    Ardan, Taras (UEM-P)
    Čejka, Čestmír (UEM-P) RID
    Luyckx, J. (FR)
    Source TitleGraefes Archive for Clinical and Experimental Ophthalmology - ISSN 0721-832X
    Roč. 249, č. 8 (2011), s. 1185-1194
    Number of pages10 s.
    Languageeng - English
    CountryDE - Germany
    KeywordsUVB-induced damage ; Corneal epithelium ; Trehalose effects
    Subject RIVFF - HEENT, Dentistry
    R&D ProjectsGPP302/10/P155 GA ČR - Czech Science Foundation (CSF)
    CEZAV0Z50390512 - UEM-P (2005-2011)
    UT WOS000293642300010
    DOI10.1007/s00417-011-1676-y
    AnnotationTrehalose, a nonreducing disaccharide of glucose, decreased the antioxidant/prooxidant imbalance in the corneal epithelium as well as proinflammatory cytokine and matrix metalloproteinase expression.Trehalose enables corneal healing through the suppression of the corneal antioxidant/prooxidant imbalance.
    WorkplaceInstitute of Experimental Medicine
    ContactLenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218
    Year of Publishing2012
Number of the records: 1  

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