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Cruciform structures are a common DNA feature important for regulating biological processes
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SYSNO ASEP 0365821 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Cruciform structures are a common DNA feature important for regulating biological processes Author(s) Brázda, Václav (BFU-R) RID, ORCID
Laister, R.C. (CA)
Jagelská, Eva (BFU-R)
Arrowsmith, Ch. (CA)Number of authors 4 Source Title B M C Molecular Biology - ISSN 1471-2199
Roč. 12, č. 33 (2011), s. 1-16Number of pages 16 s. Language eng - English Country GB - United Kingdom Keywords cruciform structure ; inverted repeat ; protein-DNA binding Subject RIV BO - Biophysics R&D Projects GAP301/10/1211 GA ČR - Czech Science Foundation (CSF) LC06035 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z50040507 - BFU-R (2005-2011) AV0Z50040702 - BFU-R (2007-2013) UT WOS 000294997200001 DOI 10.1186/1471-2199-12-33 Annotation DNA cruciforms play an important role in the regulation of natural processes involving DNA. These structures are formed by inverted repeats, and their stability is enhanced by DNA supercoiling. Cruciform structures are fundamentally important for a wide range of biological processes, including replication, regulation of gene expression, nucleosome structure and recombination. They also have been implicated in the evolution and development of diseases including cancer, Werner's syndrome and others. Workplace Institute of Biophysics Contact Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244 Year of Publishing 2012
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