Number of the records: 1

Local metabolism of glucocorticoids in Prague hereditary hypertriglyceridemic rats – Effect of hypertriglyceridemia and gender

SYSNO ASEP	0364679
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Local metabolism of glucocorticoids in Prague hereditary hypertriglyceridemic rats – Effect of hypertriglyceridemia and gender
Author(s)	Klusoňová, Petra (FGU-C)_{RID, ORCID} Pátková, Lenka (FGU-C) Ergang, Peter (FGU-C)_{RID, ORCID} Mikšík, Ivan (FGU-C)_{RID, ORCID, SAI} Zicha, Josef (FGU-C)_{RID, ORCID, SAI} Kuneš, Jaroslav (FGU-C)_{RID, ORCID} Pácha, Jiří (FGU-C)_{RID, ORCID}
Source Title	Steroids. - : Elsevier - ISSN 0039-128X Roč. 76, č. 12 (2011), s. 1252-1259
Number of pages	8 s.
Language	eng - English
Country	US - United States
Keywords	11beta-hydroxysteroid dehydrogenase ; glucocorticoids ; hypertriglyceridemia
Subject RIV	ED - Physiology
R&D Projects	GA305/08/0139 GA ČR - Czech Science Foundation (CSF)
	KJB500110703 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
CEZ	AV0Z50110509 - FGU-C (2005-2011)
UT WOS	000295745500005
DOI	10.1016/j.steroids.2011.06.003
Annotation	We studied local metabolism of glucocorticoids in connection with metabolic syndrome. Local metabolism of glucocorticoids is represented by 11beta-HSD1. 11beta-HSD1 activity is altered in selected tissues of HHTg rats. These changes are tissue- and gender- specific. The relationship between hypertriglyceridemia and glucocorticoid action is complex
Workplace	Institute of Physiology
Contact	Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400
Year of Publishing	2012

Number of the records: 1