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Model of fasciculation and sorting in mixed populations of axons

SYSNO ASEP	0364482
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Model of fasciculation and sorting in mixed populations of axons
Author(s)	Chaudhuri, D. (DE) Borowski, P. (IN) Zápotocký, Martin (FGU-C)_{RID, ORCID}
Source Title	Physical Review E. - : American Physical Society - ISSN 1539-3755 Roč. 84, č. 2 (2011), e021908
Number of pages	18 s.
Language	eng - English
Country	US - United States
Keywords	axon guidance ; neurogenesis ; mathematical model
Subject RIV	FH - Neurology
R&D Projects	LC554 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
CEZ	AV0Z50110509 - FGU-C (2005-2011)
UT WOS	000293559200013
DOI	10.1103/PhysRevE.84.021908
Annotation	We extend a recently proposed mathematical model aiming to describe the formation of fascicles of axons during neural development. We generalize the model to adhesive interactions of finite strengths and to multiple types of axons with type-specific interactions. With distance in the direction of axon growth, the mean fascicle size and emergent time scales grow monotonically, while the degree of sorting of fascicles by axon type has a maximum at a finite distance.To understand the emergence of slow time scales, we develop an analytical framework to analyze the interaction between neighboring fascicles
Workplace	Institute of Physiology
Contact	Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400
Year of Publishing	2012

Number of the records: 1