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Oxidized Phosphatidylcholines Facilitate Phospholipid Flip-Flop in Liposomes
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SYSNO ASEP 0364475 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Oxidized Phosphatidylcholines Facilitate Phospholipid Flip-Flop in Liposomes Author(s) Volinsky, R. (FI)
Cwiklik, Lukasz (UOCHB-X) RID, ORCID
Jurkiewicz, Piotr (UFCH-W) RID, ORCID
Hof, Martin (UFCH-W) RID, ORCID
Jungwirth, Pavel (UOCHB-X) RID, ORCID
Kinnunen, P. K. J. (FI)Number of authors 6 Source Title Biophysical Journal. - : Cell Press - ISSN 0006-3495
Roč. 101, č. 6 (2011), s. 1376-1384Number of pages 9 s. Language eng - English Country US - United States Keywords lipid oxidation ; fluorescence spectroscopy ; molecular dynamics Subject RIV CC - Organic Chemistry R&D Projects LC512 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) LC06063 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) GA203/08/0114 GA ČR - Czech Science Foundation (CSF) GEMEM/09/E006 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z40550506 - UOCHB-X (2005-2011) AV0Z40400503 - UFCH-W (2005-2011) UT WOS 000295197300011 DOI 10.1016/j.bpj.2011.07.051 Annotation A combination of fluorescence spectroscopy and molecular dynamics simulations reveal that phospholipid oxidation results in a fast cross bilayer diffusion of membrane phospholipids and loss of lipid asymmetry. Workplace Institute of Organic Chemistry and Biochemistry Contact asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434 Year of Publishing 2012
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