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Urea and Guanidinium Induced Denaturation of a Trp-Cage Miniprotein

SYSNO ASEP	0364373
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Urea and Guanidinium Induced Denaturation of a Trp-Cage Miniprotein
Author(s)	Heyda, Jan (UOCHB-X) Kožíšek, Milan (UOCHB-X)_{RID, ORCID} Bednárová, Lucie (UOCHB-X)_{RID, ORCID} Thompson, G. (GB) Konvalinka, Jan (UOCHB-X)_{RID, ORCID} Vondrášek, Jiří (UOCHB-X)_{RID, ORCID} Jungwirth, Pavel (UOCHB-X)_{RID, ORCID}
Number of authors	7
Source Title	Journal of Physical Chemistry B. - : American Chemical Society - ISSN 1520-6106 Roč. 115, č. 28 (2011), s. 8910-8924
Number of pages	15 s.
Language	eng - English
Country	US - United States
Keywords	trp-cage denaturation ; urea ; guanidinium ; molecular dynamics
Subject RIV	CC - Organic Chemistry
R&D Projects	LC512 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
	GA203/08/0114 GA ČR - Czech Science Foundation (CSF)
CEZ	AV0Z40550506 - UOCHB-X (2005-2011)
UT WOS	000292893200012
DOI	10.1021/jp200790h
Annotation	Using a combination of experimental techniques and molecular dynamics simulations, we performed an extensive study of denaturation of the Trp-cage miniprotein by urea and guanidinium.
Workplace	Institute of Organic Chemistry and Biochemistry
Contact	asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434
Year of Publishing	2012

Number of the records: 1