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The efficient synthesis of 2-arylpyrimidine acyclic nucleoside phosphonates using Liebeskind-Srogl cross-coupling reaction

SYSNO ASEP	0363154
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	The efficient synthesis of 2-arylpyrimidine acyclic nucleoside phosphonates using Liebeskind-Srogl cross-coupling reaction
Author(s)	Břehová, Petra (UOCHB-X)_{RID, ORCID} Česnek, Michal (UOCHB-X)_{RID, ORCID} Dračínský, Martin (UOCHB-X)_{RID, ORCID} Holý, Antonín (UOCHB-X) Janeba, Zlatko (UOCHB-X)_{RID, ORCID}
Number of authors	5
Source Title	Tetrahedron. - : Elsevier - ISSN 0040-4020 Roč. 67, č. 38 (2011), s. 7379-7385
Number of pages	7 s.
Language	eng - English
Country	GB - United Kingdom
Keywords	Liebeskind-Srogl cross-coupling ; acyclic nucleoside phosphonates ; pyrimidines ; arylboronic acids ; microwave
Subject RIV	CC - Organic Chemistry
R&D Projects	1M0508 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
CEZ	AV0Z40550506 - UOCHB-X (2005-2011)
UT WOS	000294593400026
DOI	10.1016/j.tet.2011.07.040
Annotation	A series of novel acyclic nucleoside phosphonates with various aryls attached to the C-2 position of the pyrimidine moiety has been prepared using the Liebeskind-Srogl cross-coupling protocol. The reactions of highly functionalised 2-(methylsulfanyl)pyrimidines with various arylboronic acids were studied and optimised.
Workplace	Institute of Organic Chemistry and Biochemistry
Contact	asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434
Year of Publishing	2012

Number of the records: 1