Number of the records: 1  

Role of Intestinal Bacteria in Gliadin-Induced Changes in Intestinal Mucosa: Study in Germ-Free Rats

  1. 1.
    SYSNO ASEP0360844
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JČlánek ve WOS
    TitleRole of Intestinal Bacteria in Gliadin-Induced Changes in Intestinal Mucosa: Study in Germ-Free Rats
    Author(s) Cinová, Jana (MBU-M)
    De Palma, G. (ES)
    Štěpánková, Renata (MBU-M) RID
    Kofroňová, Olga (MBU-M) RID, ORCID
    Kverka, Miloslav (MBU-M) RID, ORCID
    Sanz, Y. (ES)
    Tučková, Ludmila (MBU-M) RID
    Source TitlePLoS ONE. - : Public Library of Science - ISSN 1932-6203
    Roč. 6, č. 1 (2011), s. 1-10
    Number of pages10 s.
    Languageeng - English
    CountryUS - United States
    KeywordsCELIAC-DISEASE ; ALTERED EXPRESSION ; MATRIX METALLOPROTEINASES
    Subject RIVEC - Immunology
    R&D ProjectsGA310/07/0414 GA ČR - Czech Science Foundation (CSF)
    GA303/08/0367 GA ČR - Czech Science Foundation (CSF)
    GPP304/10/P406 GA ČR - Czech Science Foundation (CSF)
    IAA500200801 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
    IAA500200710 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
    KJB500200904 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
    2B06155 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
    CEZAV0Z50200510 - MBU-M (2005-2011)
    UT WOS000286515000024
    DOI10.1371/journal.pone.0016169
    AnnotationBackground and Aims: Celiac disease (CD) is a chronic inflammatory disorder of the small intestine that is induced by dietary wheat gluten proteins (gliadins) in genetically predisposed individuals. The overgrowth of potentially pathogenic bacteria and infections has been suggested to contribute to CD pathogenesis. We aimed to study the effects of gliadin and various intestinal bacterial strains on mucosal barrier integrity, gliadin translocation, and cytokine production
    WorkplaceInstitute of Microbiology
    ContactEliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231
    Year of Publishing2012
Number of the records: 1  

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