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Japanese encephalitis virus: from genome to infectome
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SYSNO ASEP 0359440 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Japanese encephalitis virus: from genome to infectome Author(s) Unni, S. K. (IN)
Růžek, Daniel (BC-A) RID, ORCID
Chhatbar, C. (IN)
Mishra, R. (IN)
Johri, M. K. (IN)
Singh, S. K. (IN)Source Title Microbes and Infection. - : Elsevier - ISSN 1286-4579
Roč. 13, č. 4 (2011), 312-321Number of pages 10 s. Language eng - English Country NL - Netherlands Keywords Japanese encephalitis ; Neurotropic infection ; Neuropathogenesis ; Mosquito borne infections ; Arboviral infections Subject RIV EE - Microbiology, Virology CEZ AV0Z60220518 - PAU-O, BC-A (2005-2011) UT WOS 000289186600003 DOI 10.1016/j.micinf.2011.01.002 Annotation Japanese encephalitis virus (JEV) is an arbovirus belonging to the family Flaviviridae. It is maintained in a zoonotic cycle involving pigs, ardeid birds and Culex species of mosquitoes. Humans are accidental/dead end hosts of JEV infection because they cannot sustain high viral titers. Factors affecting the clinical manifestations and pathogenesis of JEV infection are not well understood. Though, vaccines are currently available against JEV, it has to be further improved. Here we review the literature on the JEV life cycle, pathogenesis and host immune responses to JEV infection. Workplace Biology Centre (since 2006) Contact Dana Hypšová, eje@eje.cz, Tel.: 387 775 214 Year of Publishing 2012
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