Number of the records: 1
Automatic Formation of Hypotheses on the Relationships between Structure of Naphthalene Analogs and Bioluminescence Response of Bioreporter Pseudomonas fluorescens HK44
- 1.
SYSNO ASEP 0359054 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Automatic Formation of Hypotheses on the Relationships between Structure of Naphthalene Analogs and Bioluminescence Response of Bioreporter Pseudomonas fluorescens HK44 Author(s) Trögl, J. (CZ)
Hálová, J. (CZ)
Kuncová, Gabriela (UCHP-M) RID, SAI
Pařík, P. (CZ)Source Title Folia Microbiologica. - : Springer - ISSN 0015-5632
Roč. 55, č. 5 (2010), s. 411-417Number of pages 7 s. Language eng - English Country CZ - Czech Republic Keywords substituted naphthalenes ; bioconversion ; optical biosensor Subject RIV CE - Biochemistry R&D Projects OC 121 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z40720504 - UCHP-M (2005-2011) UT WOS 000282873200001 DOI 10.1007/s12223-010-0069-7 Annotation Seven hypotheses on relationships between the structure of naphthalene analogs and bioluminescence response of bioreporter Pseudomonas fluorescens were formulated using GUHA (General Unary Hypotheses Automaton) on a training set of 37 compounds. Prediction of bioluminescence response of 12 new naphthalene analogs was successful in 69 % cases and resulted in rejection of single hypothesis. The results demonstrate applicability of GUHA in structure-activity research, especially for qualitative data. Workplace Institute of Chemical Process Fundamentals Contact Eva Jirsová, jirsova@icpf.cas.cz, Tel.: 220 390 227 Year of Publishing 2012
Number of the records: 1