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8-Aza-7,9-dideazaxanthine acyclic nucleoside phosphonate inhibitors of thymidine phosphorylase
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SYSNO ASEP 0359018 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title 8-Aza-7,9-dideazaxanthine acyclic nucleoside phosphonate inhibitors of thymidine phosphorylase Author(s) Mařák, David (UOCHB-X) RID
Otmar, Miroslav (UOCHB-X) RID
Votruba, Ivan (UOCHB-X) RID
Dračínský, Martin (UOCHB-X) RID, ORCID
Krečmerová, Marcela (UOCHB-X) RID, ORCIDNumber of authors 5 Source Title Bioorganic and Medicinal Chemistry Letters. - : Elsevier - ISSN 0960-894X
Roč. 21, č. 2 (2011), s. 652-654Number of pages 3 s. Language eng - English Country GB - United Kingdom Keywords 8-aza-7,9-dideazaxanthine ; pyrrolo[3,4-d]pyrimidine ; nucleotide analog Subject RIV CC - Organic Chemistry R&D Projects 1M0508 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z40550506 - UOCHB-X (2005-2011) UT WOS 000285998000006 DOI 10.1016/j.bmcl.2010.12.027 Annotation 3- and 8-(8-phosphonooctyl)-8-aza-7,9-dideazaxanthine, and 1,8-bis(8-aza-7,9-dideazaxanthin-8-yl)octane were prepared and found to inhibit bacterial and human thymidine phosphorylase. Workplace Institute of Organic Chemistry and Biochemistry Contact asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434 Year of Publishing 2012
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