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Walking of antitumor bifunctional trinuclear PtII complex on double-helical DNA
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SYSNO ASEP 0358135 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Walking of antitumor bifunctional trinuclear PtII complex on double-helical DNA Author(s) Malina, Jaroslav (BFU-R) ORCID
Kašpárková, J. (CZ)
Farrell, N.P. (US)
Brabec, Viktor (BFU-R) RID, ORCIDNumber of authors 4 Source Title Nucleic Acids Research. - : Oxford University Press - ISSN 0305-1048
Roč. 39, č. 2 (2011), s. 720-728Number of pages 9 s. Language eng - English Country GB - United Kingdom Keywords BBR3464 ; DNA ; cross-link Subject RIV BO - Biophysics R&D Projects ME08017 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) OC08003 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) IAA400040803 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) ME10066 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z50040507 - BFU-R (2005-2011) AV0Z50040702 - BFU-R (2007-2013) UT WOS 000286675300035 DOI 10.1093/nar/gkq803 Annotation The results show that cross-links originally formed by BBR3464 in one strand of DNA can spontaneously translocate from one DNA strand to its complementary counterpart, which may evoke walking of the platinum complex on DNA molecule. Workplace Institute of Biophysics Contact Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244 Year of Publishing 2011
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