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Mutant genetic background affects the functional rearrangement and kinetic properties of JMJD2b histone demethylase
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SYSNO ASEP 0357399 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Mutant genetic background affects the functional rearrangement and kinetic properties of JMJD2b histone demethylase Author(s) Bártová, Eva (BFU-R) ORCID
Stixová, Lenka (BFU-R) RID, ORCID
Galiová-Šustáčková, Gabriela (BFU-R)
Harničarová, Andrea (BFU-R) ORCID
Legartová, Soňa (BFU-R) ORCID
Kozubek, Stanislav (BFU-R) RIDNumber of authors 6 Source Title Journal of Molecular Biology. - : Elsevier - ISSN 0022-2836
Roč. 405, č. 3 (2011), s. 679-695Number of pages 17 s. Language eng - English Country GB - United Kingdom Keywords histone code ; SUV39h ; JMJ2b Subject RIV BO - Biophysics R&D Projects GAP302/10/1022 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50040507 - BFU-R (2005-2011) AV0Z50040702 - BFU-R (2007-2013) UT WOS 000286788200006 DOI 10.1016/j.jmb.2010.11.001 Annotation We have studied dynamics of JMJD2b histone demethylases, which functional characteristics are different in mutant and truncated variants. Important changes in nuclear distribution and kinetics of JMJD2b were observed in prostate cancer cells in comparison with other tumor cells and fibroblasts. Workplace Institute of Biophysics Contact Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244 Year of Publishing 2011
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