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Structural Insights into the Function of P2X4: An ATP-Gated Cation Channel of Neuroendocrine Cells
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SYSNO ASEP 0355649 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Structural Insights into the Function of P2X4: An ATP-Gated Cation Channel of Neuroendocrine Cells Author(s) Stojilkovic, S. S. (US)
Yan, Z. (US)
Obšil, T. (CZ)
Zemková, Hana (FGU-C) RID, ORCIDSource Title Cellular and Molecular Neurobiology. - : Springer - ISSN 0272-4340
Roč. 30, č. 8 (2010), s. 1251-1258Number of pages 8 s. Language eng - English Country US - United States Keywords ATP-gated receptor channels ; gating ; ivermectin Subject RIV ED - Physiology R&D Projects IAA500110910 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) IAA501110801 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z50110509 - FGU-C (2005-2011) UT WOS 000285947200016 DOI 10.1007/s10571-010-9568-y Annotation The P2X4 receptor is a member of a family of ATP-gated cation channels, which are composed of three subunits, each having two transmembrane domains linked by a large extracellular loop and intracellularly located N- and C-termini. Recent crystallization of zebrafish P2X4 not only provided the possibility for re-interpretation of data generated by site-directed mutagenesis but also to progress in further work on structural-functional characterization Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2011
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