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Knockdown of F1 epsilon subunit decreases mitochondrial content of ATP synthase and leads to accumulation of subunit c
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SYSNO ASEP 0355560 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Knockdown of F1 epsilon subunit decreases mitochondrial content of ATP synthase and leads to accumulation of subunit c Author(s) Havlíčková, Vendula (FGU-C)
Kaplanová, Vilma (FGU-C) RID, ORCID
Nůsková, Hana (FGU-C) RID, ORCID
Drahota, Zdeněk (FGU-C) RID, ORCID
Houštěk, Josef (FGU-C) RID, ORCIDSource Title Biochimica Et Biophysica Acta-Bioenergetics. - : Elsevier - ISSN 0005-2728
Roč. 1797, 6-7 (2010), s. 1124-1129Number of pages 6 s. Action European Bioenergetics Conference /16./ Event date 17.07.2010-22.07.2010 VEvent location Warsaw Country PL - Poland Event type EUR Language eng - English Country NL - Netherlands Keywords ATP synthase ; biogenesis ; mitochondria Subject RIV EB - Genetics ; Molecular Biology R&D Projects 1M0520 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) NS9759 GA MZd - Ministry of Health (MZ) CEZ AV0Z50110509 - FGU-C (2005-2011) UT WOS 000279663200063 DOI 10.1016/j.bbabio.2009.12.009 Annotation Silencing in HEK293 cell line by RNAi of ATP5E gene encoding the epsilon subunit resulted in inhibition of biogenesis of ATP synthase and accumulation of hydrophobic subunit c of the rotor structure of the enzyme. Results indicate a regulatory role of the smallest subunit of the catalytic F1 part of the enzyme in biosynthesis and assembly of mammalian ATP synthase complex Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2011
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